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Low Dose Naltrexone (LDN)

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4 FAQs

Low Dose Naltrexone (LDN) is a unique therapy that works by gently modulating the immune system and promoting balance in the body. Unlike standard doses of naltrexone (used to treat opioid or alcohol dependence), LDN is administered at very small doses to help reduce inflammation, regulate immune function, and support overall wellness.

LDN is increasingly used in chronic pain management, autoimmune conditions, and anti-inflammatory protocols, offering patients a safe, well-tolerated option to improve quality of life.

Low Dose Naltrexone (LDN)

Treatments (0)

Advice for Low Dose Naltrexone (LDN)

LDN may be considered if you are experiencing:

  • Chronic pain or fibromyalgia
  • Autoimmune conditions (thyroid disorders, multiple sclerosis, rheumatoid arthritis, Crohn’s disease, lupus)
  • Persistent fatigue or low energy
  • Inflammation-related health concerns
  • Mood disorders, anxiety, or depression linked to immune imbalance
  • Poor sleep quality or stress-related symptoms
  • Immune Modulation: LDN works by temporarily blocking opioid receptors, which triggers the body to increase endorphin production. These endorphins play a key role in regulating the immune system and reducing inflammation.
  • Low Dose Benefits: At these small doses, LDN does not act like traditional naltrexone therapy — instead, it provides a gentle, balancing effect with minimal side effects.
  • Administration: Taken as oral capsule often compounded for individualized dosing.

Potential Benefits May Include:

  • Reduced inflammation and pain
  • Improved energy and stamina
  • Better sleep quality
  • Enhanced mood and mental clarity
  • Immune system balance for autoimmune conditions

Alongside LDN therapy, patients can maximize long-term wellness and reduce inflammation by:

  • Following an anti-inflammatory diet (rich in whole foods, omega-3s, and antioxidants)
  • Staying physically active and maintaining a healthy weight
  • Practicing stress reduction techniques (yoga, meditation, mindfulness)
  • Getting high-quality sleep and proper recovery
  • Avoiding smoking, excessive alcohol, and processed foods

Low Dose Naltrexone (LDN) FAQs (4)

LDN is commonly used off-label to support immune system balance, reduce chronic inflammation, and help manage various autoimmune or pain-related conditions.

At low doses, naltrexone temporarily blocks opioid receptors, triggering the body to increase natural endorphin production. This may help regulate the immune response and reduce inflammation.

LDN is often used by individuals with autoimmune conditions, chronic pain, fibromyalgia, multiple sclerosis, and other inflammatory issues. Always consult a healthcare provider for personalized guidance.

Most people tolerate LDN well. Some may experience vivid dreams, mild sleep disturbances, or headaches during the first few days. These symptoms are usually temporary.